INCIDENCE, INDICATIONS, RISK FACTORS, AND OUTCOMES OF EMERGENCY PERIPARTUM HYSTERECTOMY WORLDWIDE: A SYSTEMATIC REVIEW
DOI:
https://doi.org/10.53555/nnmhs.v9i8.1791Keywords:
Incidence, Indications, Risk factor, Outcomes, Emergency HysterectomyAbstract
Objective: The objective of this study is to provide a comprehensive analysis of the occurrence, indications, risk factors, outcomes, and management strategies associated with emergency peripartum hysterectomy on a global scale. Additionally, this study aims to compare the outcomes of this procedure across various income situations.
Methods: A systematic search strategy was conducted across several electronic reference databases: PubMed, MEDLINE, EMBASE, ClinicalTrials.gov, Cochrane Library, Web of Science, and Emcare databases up to August 3, 2023. Duplicate publications, review articles, editorials, and incomplete articles were excluded.
Results: This study presents an updated version of a previously conducted systematic review, which was originally published in 2016. The inclusion criteria for this study encompassed reports that provided data on the occurrence of emergency peripartum hysterectomy. Emergency peripartum hysterectomy was operationally defined as the surgical extraction of the uterus due to severe obstetric problems within a period of up to 6 weeks following childbirth. The process of title and abstract screening, as well as full-text review, was conducted with Endnote data management software. Out of a total of 8,775 papers that were reviewed, a subset of 26 articles published after the year 2015 were deemed eligible for inclusion. Consequently, the overall number of studies included in the analysis amounted to 154.
Conclusion: There are significant variations in the occurrence of emergency peripartum hysterectomy across different income contexts. Women residing in lower-income settings face an elevated likelihood of experiencing emergency peripartum hysterectomy, as well as a greater burden of associated morbidity and mortality. The incidence of emergency peripartum hysterectomy is expected to rise because to the escalating prevalence of caesarean deliveries.
References
Van Den Akker T, Brobbel C, Dekkers OM, Bloemenkamp KWM. Prevalence, Indications, Risk Indicators, and Outcomes of Emergency Peripartum Hysterectomy Worldwide: A Systematic Review and Meta-analysis. Vol. 128, Obstetrics and Gynecology. 2016.
Huque S, Roberts I, Fawole B, Chaudhri R, Arulkumaran S, Shakur-Still H. Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: Analysis of data from the WOMAN trial. BMC Pregnancy Childbirth. 2018;18(1).
Rossi AC, Lee RH, Chmait RH. Emergency postpartum hysterectomy for uncontrolled postpartum bleeding: A systematic review. Vol. 115, Obstetrics and Gynecology. 2010.
Geller SE, Koch AR, Garland CE, MacDonald EJ, Storey F, Lawton B. A global view of severe maternal morbidity: Moving beyond maternal mortality. Vol. 15, Reproductive Health. 2018.
Say L, Pattinson RC, Gülmezoglu AM. WHO systematic review of maternal morbidity and mortality: The prevalence of severe acute maternal morbidity (near miss). Vol. 1, Reproductive Health. 2004.
Sharma B, Sikka P, Jain V, Jain K, Bagga R, Suri V. Peripartum hysterectomy in a tertiary care hospital: Epidemiology and outcomesImproving outcomes for peripartum hysterectomy: Still a long way to go! J Anaesthesiol Clin Pharmacol. 2017;33(3).
Akintayo AA, Olagbuji BN, Aderoba AK, Akadiri O, Olofinbiyi BA, Bakare B. Emergency Peripartum Hysterectomy: A Multicenter Study of Incidence, Indications and Outcomes in Southwestern Nigeria. Matern Child Health J. 2016;20(6).
Jakobsson M, Tapper AM, Colmorn LB, Lindqvist PG, Klungsøyr K, Krebs L, et al. Emergency peripartum hysterectomy: Results from the prospective Nordic Obstetric Surveillance Study (NOSS). Acta Obstet Gynecol Scand. 2015;94(7).
Kallianidis AF, Maraschini A, Danis J, Colmorn LB, Deneux-Tharaux C, Donati S, et al. Epidemiological analysis of peripartum hysterectomy across nine European countries. Acta Obstet Gynecol Scand. 2020;99(10).
Cheng HC, Pelecanos A, Sekar R. Review of peripartum hysterectomy rates at a tertiary Australian hospital. Aust New Zeal J Obstet Gynaecol. 2016;56(6).
Balalau D-O, Sima RM, Bacalbasa N, Ples L, Stanescu AD. Emergency Peripartum Hysterectomy, Physical and Mental Consequences: a 6-Years Study. J Mind Med Sci. 2016;3(1).
Govindappagari S, Wright JD, Ananth C V., Huang Y, D’Alton ME, Friedman AM. Risk of Peripartum Hysterectomy and Center Hysterectomy and Delivery Volume. Obstet Gynecol. 2016;128(6).
Campbell SM, Corcoran P, Manning E, Greene RA. Peripartum hysterectomy incidence, risk factors and clinical characteristics in Ireland. Eur J Obstet Gynecol Reprod Biol. 2016;207.
Arulpragasam K, Hyanes G, Epee-Bekima M. Emergency peripartum hysterectomy in a Western Australian population: Ten-year retrospective case-note analysis. Aust New Zeal J Obstet Gynaecol. 2019;59(4):533–7.
Lauroy A, Verhaeghe C, Vidal F, Parant O, Legendre G, Guerby P. Perioperative outcomes using LigaSure compared with conventional technique in peripartum hysterectomy. Arch Gynecol Obstet. 2020;301(1).
De Gregorio A, Friedl TWP, Scholz C, Janni W, Ebner F, De Gregorio N. Emergency peripartal hysterectomy-a single-center analysis of the last 13 years at a tertiary perinatal care unit. J Perinat Med. 2019;47(2).
Maraschini A, Lega I, D’Aloja P, Buoncristiano M, Dell’Oro S, Donati S, et al. Women undergoing peripartum hysterectomy due to obstetric hemorrhage: A prospective population-based study. Acta Obstet Gynecol Scand. 2020;99(2).
MK UE, MS W, J A. AN assessment of extent and associated factors of obstetric hysterectomy and its association with mortality and morbidity. Indo Am J Pharm Sci. 2019;6:6765–9.
Triunfo S, Ferrazzani S, Volpe M, Scambia G, Lanzone A. Old and novel insights into emergency peripartum hysterectomy: a time-trend analysis. Arch Gynecol Obstet. 2020;301(5).
Bolnga JW, Mola GDL, Ao P, Sapau W, Verave O, Lufele E, et al. Mortality and morbidity after emergency peripartum hysterectomy in a provincial referral hospital in Papua New Guinea: A seven-year audit. Aust New Zeal J Obstet Gynaecol. 2021;61(3).
Chaudhary V, Singh M, Nain S, Reena F, Aggarwal K, Biswas R, et al. Incidence, Management and Outcomes in Women Undergoing Peripartum Hysterectomy in a Tertiary Care Centre in India. Cureus. 2021;
Mbakwa MR, Tendongfor N, Ngunyi YL, Ngek ESN, Alemkia F, Egbe TO. Indications and outcomes of emergency obstetric hysterectomy; a 5-year review at the Bafoussam Regional Hospital, Cameroon. BMC Pregnancy Childbirth. 2021;21(1).
Yildirim GY, Koroglu N, Akca A, Talmac M, Dikmen S, Yıldırım G, et al. What is new in peripartum hysterectomy? A seventeen year experience in a tertiary hospital. Taiwan J Obstet Gynecol. 2021;60(1).
Rawashdeh H, Obeidat R, Masaadeh L. Emergency peripartum hysterectomy in a tertiary teaching hospital in Northern Jordan: a 15-year review. Gynecol Surg. 2021;18(1).
Chawla J, Arora CD, Paul M, Ajmani SN. Emergency obstetric hysterectomy: A retrospective study from a teaching hospital in north India over eight years. Oman Med J. 2015;30(3).
Zhang Y, Yan J, Han Q, Yang T, Cai L, Fu Y, et al. Emergency obstetric hysterectomy for life-threatening postpartum hemorrhage. Vol. 96, Medicine (United States). 2017.
Senturk MB, Cakmak Y, Guraslan H, Dogan K. Emergency peripartum hysterectomy: 2-year experiences in nontertiary center. Arch Gynecol Obstet. 2015;292(5).
Tahaoglu AE, Balsak D, Togrul C, Obut M, Tosun O, Cavus Y, et al. Emergency peripartum hysterectomy: our experience. Ir J Med Sci. 2016;185(4).
Özcan HÇ, Uğur MG, Balat Ö, Bayramoğlu Tepe N, Sucu S. Emergency peripartum hysterectomy: single center ten-year experience. J Matern Neonatal Med. 2017;30(23).
Pan XY, Wang YP, Zheng Z, Tian Y, Hu YY, Han SH. A marked increase in obstetric hysterectomy for placenta accreta. Chin Med J (Engl). 2015;128(16).
Heitkamp A, Seinstra J, van den Akker T, Vollmer L, Gebhardt S, van Roosmalen J, et al. A district-wide population-based descriptive study of emergency peripartum hysterectomy in a middle-income country. Int J Gynecol Obstet. 2019;146(1).
de la Cruz CZ, Thompson EL, O’Rourke K, Nembhard WN. Cesarean section and the risk of emergency peripartum hysterectomy in high-income countries: a systematic review. Vol. 292, Archives of Gynecology and Obstetrics. 2015.
Machado LSM. Emergency peripartum hysterectomy: Incidence, indications, risk factors and outcome. Vol. 3, North American Journal of Medical Sciences. 2011.
Silver RM, Landon MB, Rouse DJ, Leveno KJ, Spong CY, Thom EA, et al. Maternal morbidity associated with multiple repeat cesarean deliveries. Obstet Gynecol. 2006;107(6).
Goldenberg RL, McClure EM, Saleem S. Improving pregnancy outcomes in low- and middle-income countries. Vol. 15, Reproductive Health. 2018.
Collis R, Guasch E. Managing major obstetric haemorrhage: Pharmacotherapy and transfusion. Vol. 31, Best Practice and Research: Clinical Anaesthesiology. 2017.
Kong CW, To WWK. Trends in conservative procedures and peripartum hysterectomy rates in severe postpartum haemorrhage. J Matern Neonatal Med. 2018;31(21).
Sobhy S, Arroyo-Manzano D, Murugesu N, Karthikeyan G, Kumar V, Kaur I, et al. Maternal and perinatal mortality and complications associated with caesarean section in low-income and middle-income countries: a systematic review and meta-analysis. Lancet. 2019;393(10184).
Shukla V V., Carlo WA. Review of the evidence for interventions to reduce perinatal mortality in low- and middleincome countries. Vol. 7, International Journal of Pediatrics and Adolescent Medicine. 2020.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Licensing
Ninety Nine Publication publishes articles under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This licensing allows for any use of the work, provided the original author(s) and source are credited, thereby facilitating the free exchange and use of research for the advancement of knowledge.
Detailed Licensing Terms
Attribution (BY): Users must give appropriate credit, provide a link to the license, and indicate if changes were made. Users may do so in any reasonable manner, but not in any way that suggests the licensor endorses them or their use.
No Additional Restrictions: Users may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
