THE IMPACT OF COMORBIDITIES ON COVID-19 SEVERITY IN PEDIATRIC PATIENTS: A SYSTEMATIC REVIEW
DOI:
https://doi.org/10.53555/nnmhs.v9i7.1750Keywords:
Comorbidity, COVID-19, novel coronavirus, pediatric, SARS-CoV-2Abstract
Background: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2), has caused over 6 million deaths worldwide. Comorbidities like obesity, asthma, and neurological disorders are risk factors for severe illness in pediatric patients. The direct impact of COVID-19 on child mortality is limited, with only 0.4% of deaths occurring in children under 20.
Objective: To identify risk factors and potential interventions to reduce severe illness and mortality in pediatric patients.
Methods: A systematic review of COVID-19, sars-cov-2, and novel coronavirus in children was conducted using PubMed and Google Scholar. Severe COVID-19 prevalence in children assessed using Strengthening the Reporting of Observational Studies in Epidemiology (STROME) and the Joanna Briggs Institute (JBI) checklists, assessing quality and bias.
Results: A review of 41 studies found a significant difference in severe COVID-19 infection risk among children with and without comorbidities, including hematologic, immune, respiratory, cardiovascular, neurological, obesity, and genetic syndromes.
Conclusion: Comorbidities in pediatric COVID-19 patients enhance the risk; vaccinations and increased vigilance should take priority.
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