PERIOPERATIVE ANTIBIOTIC PROPHYLAXIS IN UROLOGICAL SURGERY: AN UPDATE SYSTEMATIC REVIEW

Authors

  • Bayu Kusumo Faculty of Medicine, Indonesian Islamic University, Indonesia Author
  • Inannami Fadiyah Mahrunnisa Faculty of Medicine, Indonesian Islamic University, Indonesia Author

DOI:

https://doi.org/10.61841/bxrr1q86

Keywords:

Perioperative, antibiotic prophylaxis, urological surgery

Abstract

Background: Perioperative antibiotic prophylaxis (PAP) is provided to avoid local or systemic infections, such as surgical site infections (SSI), urinary tract infections (UTI), or sepsis. However, PAP may not be effective in reducing symptomatic UTI in some procedures, such as extracorporeal shock wave lithotripsy and cystoscopy.

The aim: This study aims to determine the effectiveness of perioperative antibiotic prophylaxis in urological surgery.

Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and MetaAnalysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SAGEPUB, and ScienceDirect, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.

Results: In the PubMed database, the results of our search brought up 105 articles, whereas the results of our search on SAGEPUB brought up 6 articles, our search on ScienceDirect brought up 129 articles. In the end, we compiled 9 papers, 7 of which came from PubMed, and 2 of which came from ScienceDirect. We included nine research that met the criteria.

Conclusion: Perioperative antibiotic prophylaxis (PAP) can lower SSI, UTI, and sepsis incidences in urological surgery. In addition, PAP showed a lower positive blood culture. To minimize side effects and lower the risk of drug-resistant organisms, the use of reasonable PAP is advised.

References

Chung DY, Lee JY. Recommendations for Antibacterial Prophylaxis in Endourological Procedures. Urogenital Tract Infection. 2019;14(1):1.

Baas W, Parker A, Radadia K, Ogawa S, Vetter J, Paradis A, et al. Antibiotic Duration After Urethroplasty: An Attempt at Improving Antibiotic Stewardship. Urology. 2021 Dec 1;158:228–31.

Ailaney N, Zielinski E, Doll M, Bearman GM, Kates SL, Golladay GJ. Variation in practice for preoperative antibiotic prophylaxis: a survey from an academic tertiary referral center in the United States. Patient Saf Surg. 2021 Dec 1;15(1).

Goldberg H, Shenhar C, Tamir H, Mano R, Baniel J, Margel D, et al. Predictors of surgical site infection after radical cystectomy: should we enhance surgical antibiotic prophylaxis? World J Urol. 2019 Jun 1;37(6):1137– 43.

Bachmann F, Adam T, Friedersdorff F, Liefeldt L, Slowinski T, Budde K, et al. Perioperative antibiotic prophylaxis in renal transplantation: a single-center comparison between two regimens and a brief survey among the Eurotransplant renal transplantation centers. World J Urol. 2019 May 1;37(5):957–67.

Hwang EC, Jung S Il, Kwon DD, Lee G, Bae JH, Na YG, et al. A prospective Korean multicenter study for infectious complications in patients undergoing prostate surgery: Risk factors and efficacy of antibiotic prophylaxis. J Korean Med Sci. 2014;29(9):1271–7.

Clark R, Violette P. Evidence-Base Urology: Antibiotic prophylaxis in urological surgery. In: Dahm P, Dmochowski RR, editors. second. John Wiley & Sons Ltd.; 2018.

Lightner DJ, Wymer K, Sanchez J, Kavoussi L. Best Practice Statement on Urologic Procedures and Antimicrobial Prophylaxis. Journal of Urology. 2020 Feb 1;203(2):351–6.

Haider M, Ladurner C, Mayr R, Tandogdu Z, Fritsche HM, Fradet V, et al. Use and duration of antibiotic prophylaxis and the rate of urinary tract infection after radical cystectomy for bladder cancer: Results of a multicentric series. Urologic Oncology: Seminars and Original Investigations. 2019 May 1;37(5):300.e9300.e15.

Grüne B, Viehweger V, Waldbillig F, Nientiedt M, Kriegmair MC, Rassweiler-Seyfried MC, et al. Preoperative urine culture – Is it necessary to prevent infectious complications following ureterorenoscopy? J Microbiol Methods. 2020 Jun 1;173.

Murakami M, Kiyota H, Kasai K, Bando S, Kira S, Koide H, et al. Antimicrobial prophylaxis for transurethral resection of bladder tumor: A retrospective comparison of preoperative single-dose administration of piperacillin and tazobactam/piperacillin. Journal of Infection and Chemotherapy. 2018 Dec 1;24(12):954–7.

Nishimura S, Wada K, Araki M, Sadahira T, Maruyama Y, Mitsui Y, et al. Use of single-dose perioperative antimicrobial therapy is acceptable in recipients of living-donor renal transplants in the rituximab era. Journal of Infection and Chemotherapy. 2019 Apr 1;25(4):247–52.

Yamamoto S, Shigemura K, Kiyota H, Arakawa S. Antimicrobial prophylaxis in urological surgery. Vol. 11, Korean Association of Urogenital Tract Infection and Inflammation. 2016. p. 77–85.

Berrondo C, Carone M, Katz C, Kenny A. Adherence to Perioperative Antibiotic Prophylaxis Recommendations and Its Impact on Postoperative Surgical Site Infections. Cureus. 2022 Jun 12;

Capocasale E, Vecchi ED, Mazzoni MP, Valle RD, Pellegrino C, Ferretti S, et al. Surgical site and early urinary tract infections in 1000 kidney transplants with antimicrobial perioperative prophylaxis. Transplant Proc. 2014;46(10):3455–8.

Davuluri M, Bernstein AP, Fram E, Watts KL. Variations in Perioperative Antibiotic Prescriptions Among Academic Urologists After Ambulatory Endoscopic Urologic Surgery: Impact on Infection Rates and Validation of 2019 Best Practice Statement. Urology. 2020 Dec 1;146:101–6.

Nayyar R, Kumar S. Peri-operative antibiotic usage during endourological surgery: A multi-institutional, national-level, cross-sectional audit of prevalent practice pattern in India. Indian Journal of Urology. 2023;39(2):133.

Schneidewind L, Torabi L, Dräger DL, Hakenberg OW. Reduction of Perioperative Antibiotic Prophylaxis in Open Radical Cystectomy with Ileal Conduit Is Feasible: Results of a Prospective Clinical Trial. Urol Int. 2022 Aug 1;106(8):825–31.

Sharma AP, Devana SK, Bora GS, Mavuduru RS, Mohan B, Taneja N, et al. Protocol-based perioperative antimicrobial prophylaxis in urologic surgeries: Feasibility and lessons learned. Indian Journal of Urology. 2019 Apr 1;35(2):141–6.

Shin B, Chung HS, Hwang EC, Jung S Il, Kwon DD. Antibiotic prophylaxis in radical prostatectomy: Comparison of 2-day and more than 2-day prophylaxis. J Korean Med Sci. 2017;32(6):1009–15.

Brocard E, Reveiz L, Régnaux JP, Abdala V, Ramón-Pardo P, Bueno A del R. Antibiotic prophylaxis for surgical procedures: A scoping review. Vol. 45, Revista Panamericana de Salud Publica/Pan American Journal of Public Health. Pan American Health Organization; 2021.

Yang HJ. Prophylactic Antimicrobial Therapy and Antimicrobial Stewardship in Urologic Surgery. Urogenit Tract Infect [Internet]. 2023;18(1):8–14. Available from: http://crossmark.crossref.org/dialog/?doi=10.14777/uti.2023.18.1.8&domain=pdf&date_stamp=2023-4-30

De Vermandois JAR, Cochetti G, Del Zingaro M, Santoro A, Panciarola M, Boni A, et al. Evaluation of surgical site infection in mini-invasive urological surgery. Open Medicine (Poland). 2019;14(1):711–8.

Herman TF, Bordoni B. Wound Classification [Internet]. StatPearls. 2023 [cited 2024 Mar 18]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554456/

Lightner DJ, Wymer K, Sanchez J, Kavoussi L. Urologic Procedures and Antimicrobial Prophylaxis [Internet]. American Urological Association. [cited 2024 Mar 18]. Available from: https://www.auanet.org/guidelines-andquality/quality-and-measurement/quality-improvement/clinical-consensus-statement-and-quality-improvementissue-brief-(ccs-and-qiib)/urologic-procedures-and-antimicrobial-prophylaxis-(2019)

Dhole S, Mahakalkar C, Kshirsagar S, Bhargava A. Antibiotic Prophylaxis in Surgery: Current Insights and Future Directions for Surgical Site Infection Prevention. Cureus. 2023 Oct 28;

Ferroni MC, Lyon TD, Rycyna KJ, Dwyer ME, Schneck FX, Ost MC, et al. The Role of Prophylactic Antibiotics after Minimally Invasive Pyeloplasty with Ureteral Stent Placement in Children. Urology. 2016 Mar 1;89:107– 12.

Viers BR, Cockerill PA, Mehta RA, Bergstralh EJ, Krambeck AE. Extended antimicrobial use in patients undergoing percutaneous nephrolithotomy and associated antibiotic related complications. Journal of Urology. 2014 Dec 1;192(6):1667–72.

Calvert JK, Holt SK, Mossanen M, James AC, Wright JL, Porter MP, et al. Use and outcomes of extended antibiotic prophylaxis in urological cancer surgery. Journal of Urology. 2014;192(2):425–9.

Bhojani N, Eisner B, Monga M, Paranjpe R, Cutone B, Chew BH. Sepsis prevalence and associated hospital admission and mortality after ureteroscopy in employed adults. BJU Int. 2023 Aug 1;132(2):210–6.

Scotland KB, Lange D. Prevention and management of urosepsis triggered by ureteroscopy. Vol. 10, Research and Reports in Urology. Dove Medical Press Ltd.; 2018. p. 43–9.

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Published

2024-03-22

How to Cite

Kusumo, B., & Mahrunnisa , I. F. (2024). PERIOPERATIVE ANTIBIOTIC PROPHYLAXIS IN UROLOGICAL SURGERY: AN UPDATE SYSTEMATIC REVIEW. Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 10(3), 254-262. https://doi.org/10.61841/bxrr1q86

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