EARLY OPERATIVE MANAGEMENT OF COMPLICATED APPENDICITIS IS ASSOCIATED WITH IMPROVED SURGICAL OUTCOMES IN ADULTS: A SYSTEMATIC REVIEW
DOI:
https://doi.org/10.53555/nx04dk77Keywords:
Complicated appendicitis, Operative management, OutcomesAbstract
Introduction: Appendectomy is one of the most common surgeries in the US, with over 300,000 performed annually. In addition, 20% of adults may have complex appendicitis with extensive peritonitis, perforation, abscess, or phlegmon. In severe appendicitis patients, there is no unanimity on whether to operate or when. Statistics contradict each other. Nonoperative care and radiologically guided percutaneous drainage have become prominent treatments.
The aim: This article demonstrated an association between early surgical management of complicated appendicitis and enhanced surgical outcomes in adults.
Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and MetaAnalysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.
Result: In the PubMed database, the results of our search brought up 68 articles, whereas the results of our search on SagePub brought up 51 articles. The results of the search conducted for the last year of 2013 yielded a total 19 articles for PubMed and 13 articles for SagePub. In the end, we compiled a total of 11 papers, 7 of which came from PubMed and 4 of which came from SagePub. We included three study that met the criteria.
Conclusion: The benefits of immediate surgery for patients with complicated appendicitis include a reduction in hospitalization time, subsequent infections, and short-term mortality, according to research.
References
Baird DLH; Simillis C; Kontovounisios C; et al. Acute appendicitis. BMJ. 2017;357:1–6.
Khan MS, Chaudhry MBH, Shahzad N, Tariq M, Memon WA, Alvi AR. Risk of appendicitis in patients with incidentally discovered appendicoliths. J Surg Res. Januari 2018;221:84–7.
Bhangu A, Søreide K, Di Saverio S, Assarsson JH, Drake FT. Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management. Lancet. 2015;386(10000):1278–87.
Dijk ST; Djik AH; Djikgraaf MG; et al. Meta‐analysis of in‐hospital delay before surgery as a risk factor for complications in patients with acute appendicitis. Br J Surg. 2018;105(8):933–45.
Rollins KE; Varadhan KK; Neal KR; et al. Antibiotics versus appendicectomy for the treatment of uncomplicated acute appendicitis: an updated meta‐analysis of randomised controlled trials. World J Surg. 2016;40:2305–18.
Beerle C; Gelpke H; Breitenstein S; et al. Complicated acute appendicitis presenting as a rapidly progressive soft tissue infection of the abdominal wall: a case report. J Med Case Rep. 2016;10:331.
Fauci AS, Jameson JL, Kasper D, et al. Harrison’s Principles of Internal Medicine 19th Edition. New York: McGrawHill Education; 2018.
Buckius MT, McGrath B, Monk J, Grim R, Bell T, Ahuja V. Changing Epidemiology of Acute Appendicitis in the United States: Study Period 1993–2008. J Surg Res [Internet] 2012;175(2):185–90. Tersedia pada: https://www.sciencedirect.com/science/article/pii/S0022480411006214
Solomkin JS, Mazuski JE, Bradley JS, Rodvold KA, Goldstein EJC, Baron EJ, et al. Diagnosis and Management of Complicated Intra-abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Clin Infect Dis [Internet] 15 Januari 2010;50(2):133–64. Tersedia pada: https://doi.org/10.1086/649554
Simillis C, Symeonides P, Shorthouse AJ, Tekkis PP. A meta-analysis comparing conservative treatment versus acute appendectomy for complicated appendicitis (abscess or phlegmon). Surgery [Internet] 2010;147(6):818–29. Tersedia pada: https://www.sciencedirect.com/science/article/pii/S0039606009007594
Snyder MJ, Guthrie M, Cagle S. Acute Appendicitis: Efficient Diagnosis and Management. Am Fam Physician. Juli 2018;98(1):25–33.
de Almeida Leite RM, de Souza AV, Bay CP, Cauley C, Bordeianou L, Goldstone R, et al. Delayed operative management in complicated acute appendicitis—is avoiding extended resection worth the wait? Results from a global cohort study. J Gastrointest Surg. 2022;26(7):1482–9.
Kim JY, Kim JW, Park JH, Kim BC, Yoon SN. Early versus late surgical management for complicated appendicitis in adults: a multicenter propensity score matching study. Ann Surg Treat Res. 2019;97(2):103–11.
Symer MM, Abelson JS, Sedrakyan A, Yeo HL. Early operative management of complicated appendicitis is associated with improved surgical outcomes in adults. Am J Surg. September 2018;216(3):431–7.
Helling TS, Soltys DF, Seals S. Operative versus non-operative management in the care of patients with complicated appendicitis. Am J Surg. 2017;214(6):1195–200.
Hamilton AL, Kamm MA, Ng SC, Morrison M. Proteus spp. as Putative Gastrointestinal Pathogens. Clin Microbiol Rev. Juli 2018;31(3).
Gignoux B, Blanchet M-C, Lanz T, Vulliez A, Saffarini M, Bothorel H, et al. Should ambulatory appendectomy become the standard treatment for acute appendicitis? World J Emerg Surg. 2018;13:28.
Puapong D, Lee SL, Haigh PI, Kaminski A, Liu I-LA, Applebaum H. Routine interval appendectomy in children is not indicated. J Pediatr Surg [Internet] 1 September 2007;42(9):1500–3. Tersedia pada: https://doi.org/10.1016/j.jpedsurg.2007.04.011
Wright GP, Mater ME, Carroll JT, Choy JS, Chung MH. Is there truly an oncologic indication for interval appendectomy? Am J Surg [Internet] 1 Maret 2015;209(3):442–6. Tersedia pada: https://doi.org/10.1016/j.amjsurg.2014.09.020
Quartey B. Interval appendectomy in adults: A necessary evil? J Emerg Trauma Shock [Internet] 2012;5(3). Tersedia pada: https://journals.lww.com/onlinejets/fulltext/2012/05030/interval_appendectomy_in_adults__a_necessary_evil_.2.a spx
Willemsen PJ, Hoorntje LE, Eddes E-H, Ploeg RJ. The Need for Interval Appendectomy after Resolution of an Appendiceal Mass Questioned. Dig Surg [Internet] 4 Juli 2002;19(3):216–22. Tersedia pada: https://doi.org/10.1159/000064216
Young KA, Neuhaus NM, Fluck M, Blansfield JA, Hunsinger MA, Shabahang MM, et al. Outcomes of complicated appendicitis: is conservative management as smooth as it seems? Am J Surg. 2018;215(4):586–92.
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