ULTRASONOGRAPHY IN ASYMPTOMATIC DENSE BREAST: A SYSTEMATIC REVIEW

Authors

  • Arizal Abdulloh Faculty of Medicine, University of Tanjungpura, Indonesia Author

Keywords:

Breast cacer, Dense, Mammographic, Ultrasonography

Abstract

Breast cancer is a group of abnormal cells in the breast that continue to grow in multiples. Eventually these cells form a lump in the breast. If the cancerous lump is not controlled, the cancer cells can metastasize to other parts of the body. Metastases can occur in the axillary lymph nodes or above the scapula. In addition, cancer cells can nest in the bones, lungs, liver, skin and under the skin. Ca Mamae is a malignancy of the breast tissue which can originate from the ductal or lobule epithelium. Breast cancer ranks as the second leading cause of mortality in women who have been diagnosed with the disease. According to some studies, screening women for breast cancer once a year beginning at the age of 40 can reduce the risk of dying from the disease by approximately 40 percent. It is well acknowledged that mammography is an effective screening procedure for detecting breast cancer in its early stages; yet, the test is not without its limitations, particularly for women who have dense breasts. The sensitivity of mammography is reduced when performed on people who have dense breast tissue. In addition, women who have dense breast tissue have an increased risk of getting breast cancer, despite the fact that mammography has a lower detection rate for dense breast tissue. Mammographically undetected cancer can sometimes be found in women with dense tissue by the use of ultrasound screening, which can be performed manually or automatically. Studies have shown that ultrasonography makes a significant improvement in the diagnosis of clinically significant tumors that are relatively small, predominantly invasive, and lack lymph nodes. The use of supplemental breast ultrasonography in the population of women who have mammographically dense breast tissue makes it possible to detect tiny breast tumors that would have been occult otherwise. An elevated rate of biopsies is connected with the possibility of unfavorable consequences for the women who fall into this intermediate risk category.

References

GLOBOCAN (IARC). Breast Cancer Estimated Incidence, Mortality and Prevalence Worldwide in 2012. IARC World Health Organization. 2012.

Parada H, Sun X, Tse CK, et al. Lifestyle Patterns and Survival Following Breast Cancer in the Carolina Breast Cancer Study. Epidemiology. 2019;30(1):83–92.

Narod SA. Personalised medicine and population health: breast and ovarian cancer. Hum Genet. 2018;137(10):769– 78.

Kim YJ, Lee EH, Jun JK, Shin D-R, Park YM, Kim H-W, et al. Analysis of Participant Factors That Affect the Diagnostic Performance of Screening Mammography: A Report of the Alliance for Breast Cancer Screening in Korea. Korean J Radiol. 2017;18(4):624–31.

Kim SH, Kim HH, Moon WK. Automated Breast Ultrasound Screening for Dense Breasts. Korean J Radiol. 2020 Jan;21(1):15–24.

Freer PE. Mammographic breast density: impact on breast cancer risk and implications for screening. Radiographics. 2015;35(2):302–15.

Sprague BL, Conant EF, Onega T, Garcia MP, Beaber EF, Herschorn SD, et al. Variation in mammographic breast density assessments among radiologists in clinical practice: a multicenter observational study. Ann Intern Med. 2016;165(7):457–64.

Maestro C, Cazenave F, Marcy PY, Bruneton JN, Chauvel C, Bleuse A. Systematic ultrasonography in asymptomatic dense breasts. Eur J Radiol. 1998 Feb;26(3):254–6.

Yaghjyan L, Colditz GA, Rosner B, Tamimi RM. Mammographic breast density and breast cancer risk: interactions of percent density, absolute dense, and non-dense areas with breast cancer risk factors. Breast Cancer Res Treat. 2015 Feb;150(1):181–9.

Park B, Cho HM, Lee EH, Song S, Suh M, Choi KS, et al. Does breast density measured through population-based screening independently increase breast cancer risk in Asian females? Clin Epidemiol. 2017;61–70.

Weigert J, Steenbergen S. The Connecticut experiment: the role of ultrasound in the screening of women with dense breasts. Breast J. 2012;18(6):517–22.

Mainiero MB, Moy L, Baron P, Didwania AD, Green ED, Heller SL, et al. ACR appropriateness criteria® breast cancer screening. J Am Coll Radiol. 2017;14(11):S383–90.

은혜이, 보영박, 남순김, 현주서, 경란고, 준원민, et al. The Korean guideline for breast cancer screening. J Korean Med Assoc. 2015;58(5):408–19.

Siu AL. Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement. Ann Intern Med. 2016 Feb;164(4):279–96.

Ohuchi N, Suzuki A, Sobue T, Kawai M, Yamamoto S, Zheng Y-F, et al. Sensitivity and specificityof mammography and adjunctive ultrasonography to screen for breast cancer in the Japan Strategic Anti-cancer Randomized Trial (JSTART): a randomised controlled trial. Lancet (London, England). 2016 Jan;387(10016):341–8.

Korpraphong P, Limsuwarn P, Tangcharoensathien W, Ansusingha T, Thephamongkhol K, Chuthapisith S. Improving breast cancer detection using ultrasonography in asymptomatic women with non-fatty breast density. Acta radiol [Internet] 2014 Oct 1;55(8):903–8. Available from: https://doi.org/10.1177/0284185113507711

Harada-Shoji N, Suzuki A, Ishida T, Zheng Y-F, Narikawa-Shiono Y, Sato-Tadano A, et al. Evaluation of Adjunctive Ultrasonography for Breast Cancer Detection Among Women Aged 40-49 Years With Varying Breast Density Undergoing Screening Mammography: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open [Internet] 2021 Aug 18;4(8):e2121505–e2121505. Available from: https://doi.org/10.1001/jamanetworkopen.2021.

De Vita Vt, Leeman S, Rosenberg SA. Principles and Practice of Oncology. Philadelphia: Lippincott Williams & Wilkins; 2004.

Horn L; Araujo L; Nana P; et al. Principles and Practice of Oncology. New York: McGraw-Hill Education; 2015.

Ban KA, Godellas CV. Epidemiology of breast cancer. Surg Oncol Clin N Am. 2014;23:409–22.

Veronesi U, Boyle P, Goldhirsch A, Orecchia R, Viale G. Breast Cancer. Lancet. 2005 May;365(9472):1727–41.

Stachs A, Stubert J, Reimer T, Hartmann S. Benign Breast Disease in Women. Dtsch Arztebl Int. 2019 Aug;116(33– 34):565–74.

Jochelson MS, Lobbes MBI. Contrast-enhanced mammography: state of the art. Radiology. 2021;299(1):36–48.

Purwanto H, Handojo D, Hayono SJ, et al. Panduan Penatalaksanaan Kanker Payudara. Jakarta: Peraboi; 2014.

Peraboi. Panduan Penatalaksanaan Kanker. Jakarta: Peraboi; 2020.

Thigpen D, Kappler A, Brem R. The Role of Ultrasound in Screening Dense Breasts-A Review of the Literature and Practical Solutions for Implementation. Diagnostics (Basel, Switzerland). 2018 Mar;8(1).

Downloads

Published

2023-03-10

How to Cite

Abdulloh, A. (2023). ULTRASONOGRAPHY IN ASYMPTOMATIC DENSE BREAST: A SYSTEMATIC REVIEW . Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 9(3), 21-26. https://jarmhs.com/MHS/index.php/mhs/article/view/142