ASSOCATION DIABETES MELLITUS AND CELIAC DISEASE: ASYSTEMATIC REVIEW

Authors

  • Kgs. Mahendra Effendy University of Lampung, Indonesia Author

Keywords:

Autoimmune, Celiac disease, Diabetes Mellitus, Hyperglycemia

Abstract

The incidence of diabetes mellitus, a persistent metabolic condition, has been steadily climbing at an alarming rate all over the world. This condition represents a substantial danger to the wellbeing of people living in all parts of the world. Celiac disease is an immune-mediated condition that affects a person for their entire life. It is characterized by glutentriggered inflammation and morphological damage of the small bowel mucosa in genetically susceptible individuals. Celiac disease can be prevented by avoiding foodsthat contain gluten. One of the surprising revelations that came out of this latest investigation was the realization that type 1 diabetes is significantly overrepresented in particular in males who have celiac disease. On the other hand, the prevalence of type 2 diabetes was practically identical to that of the overall Finnish population. People who have celiac disease and also have type 1 or type 2 diabetes are more likely to experiencesevere comorbidities, and type 1 diabetes is associated with a poorer rate of adherence toa gluten-free diet than celiac disease alone. 16 According to the findings of this study, patients who have type 1 diabetes have an incidence of CeD that is up to twice as high. This is connected to autoimmune disease, which is the pathophysiology of type 1 diabetesas well.

References

International Diabetes Federation. Diabetes. Brussels: IDF; 2017.

Fauci AS, Jameson JL, Kasper D, et al. Harrison’s Principles of Internal Medicine 19th Edition. New York: McGraw-Hill Education; 2018.

Fuchs V, Kurppa K, Huhtala H, Collin P, Mäki M, Kaukinen K. Factors associatedwith long diagnostic delay in celiac disease. Scand J Gastroenterol. 2014;49(11):1304–10.

Tye-Din JA, Galipeau HJ, Agardh D. Celiac Disease: A Review of Current Concepts in Pathogenesis, Prevention, and Novel Therapies. Front Pediatr. 2018;6:350–7.

Rubio-Tapia A, Murray JA. Celiac disease. Curr Opin Gastroenterol. 2010;26(2):116.

Lundin KEA, Sollid LM. Advances in coeliac disease. Curr Opin Gastroenterol. 2014;30(2):154–62.

Mustalahti K, Catassi C, Reunanen A, Fabiani E, Heier M, McMillan S, et al. Theprevalence of celiac disease in Europe: results of a centralized, international massscreening project. Ann Med. 2010;42(8):587–95.

Kabbani TA, Kelly CP, Betensky RA, Hansen J, Pallav K, Villafuerte-Gálvez JA,et al. Patients with celiac disease have a lower prevalence ofnon-insulin-dependentdiabetes mellitus and metabolic syndrome. Gastroenterology. Mei 2013;144(5):912-917.e1.

Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, Yang JHM, et al. Shared and distinct genetic variants in type 1 diabetes and celiac disease. N Engl JMed. Desember 2008;359(26):2767–77.

Kylökäs A, Kaukinen K, Huhtala H, Collin P, Mäki M, Kurppa K. Type 1 and type2 diabetes in celiac disease:

prevalence and effect on clinical and histological presentation. BMC Gastroenterol [Internet] 2016;16(1):76. Tersedia pada: https://doi.org/10.1186/s12876-016-0488-2

Kizilgul M, Ozcelik O, Beysel S, Akinci H, Kan S, Ucan B, et al. Screening for celiac disease in poorly controlled type 2 diabetes mellitus: worth it or not? BMCEndocr Disord. Oktober 2017;17(1):62.

Craig ME, Prinz N, Boyle CT, Campbell FM, Jones TW, Hofer SE, et al. Prevalence of Celiac Disease in 52,721 Youth With Type 1 Diabetes: InternationalComparison Across Three Continents. Diabetes Care [Internet] 25 Mei 2017;40(8):1034–40. Tersedia pada: https://doi.org/10.2337/dc16-2508

Deniz G, Yakut M, Tüzün Y, Tuzcu AK, Arikan S. The Prevalence of Celiac Disease in Patients with Diabetes Mellitus—The Prevalence of Celiac Disease. IntJ Clin Med. 2011;2(03):201.

Elliott DE. The Pathophysiology of Celiac Disease BT - Celiac Disease. In: Rampertab SD, Mullin GE, editor. New York, NY: Springer New York; 2014. hal.39–51. Tersedia pada: https://doi.org/10.1007/978-1-4614-85605_4

Harjutsalo V, Sund R, Knip M, Groop P-H. Incidenceoftype 1 diabetes in Finland.Jama. 2013;310(4):427–8.

Camarca ME, Mozzillo E, Nugnes R, Zito E, Falco M, Fattorusso V, et al. Celiac disease in type 1 diabetes mellitus. Ital J Pediatr. Maret 2012;38:10.

Nunes-Silva JG, Nunes VS, Schwartz RP, MLSS Trecco S, Evazian D, Correa- Giannella ML, et al. Impact of type 1 diabetes mellitus and celiac disease on nutrition and quality of life. Nutr Diabetes [Internet] 2017;7(1):e239–e239. Tersedia pada: https://doi.org/10.1038/nutd.2016.43

Elfström P, Sundström J, Ludvigsson JF. Systematic review with meta‐analysis: associations between coeliac disease and type 1 diabetes. Aliment PharmacolTher.2014;40(10):1123–32.

Lohi S, Mustalahti K, Kaukinen K, Laurila K, Collin P, Rissanen H, et al. Increasing prevalence of coeliac disease over time. Aliment Pharmacol Ther. 2007;26(9):1217–25.

Weiss B, Pinhas-Hamiel O. Celiac disease and diabetes: when to test and treat. J Pediatr Gastroenterol Nutr.

;64(2):175–9.

Holmes GKT. Coeliac disease and type 1 diabetes mellitus–the case for screening.Diabet Med. 2001;18(3):169–77.

Rewers M, Liu E, Simmons J, Redondo MJ, Hoffenberg EJ. Celiac disease associated with type 1 diabetes mellitus. Endocrinol Metab Clin. 2004;33(1):197–214.

Downloads

Published

2022-12-09

How to Cite

Effendy, K. M. (2022). ASSOCATION DIABETES MELLITUS AND CELIAC DISEASE: ASYSTEMATIC REVIEW. Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 8(12), 5-9. http://jarmhs.com/MHS/index.php/mhs/article/view/86

Similar Articles

21-30 of 201

You may also start an advanced similarity search for this article.