IXORA CHINENSIS LAMK. FLOWER EXTRACT HEALTH DRINK
DOI:
https://doi.org/10.53555/nnmhs.v2i5.629Keywords:
Ultrasonication Extraction, Phenolic content, Flavonoids, Acute Toxicity, Hematological value, Wistar White RatsAbstract
Objective: Health Drinks currently are one of the most popular demands of consumption drink product in Thailand globally. We found that many anti-aging health drink products were developed under sub- standard and did not meet the Thai FDA requirements in the area of toxicities and bioactivities. This study aimed to evaluate the anti-oxidant activities of different methods of extraction and maceration of solvents, bioactivity quantities, toxicity, active ingredients of Ixora chinensis Lamk., flower extract health drink.
Methods: We studied different methods of extraction between Ultrasonication and maceration with 40% and 50% ethyl alcohol to compare the obtained number of antioxidants in Ixora chinensis Lamk., flower extract health drink. We compared yields with different period of time and also analysis of antioxidant activities with DPPH, FRAP and ABTS methods, total phenolic compound, active ingredients by HPLC and acute toxicity analysis in white wistar rats by oral administrating of Ixora chinensis Lamk., flower extract for after 24 h and 14 d.
Result: The study revealed no signals of acute toxicity in Ixora chinensis Lamk., flower extract which consisted of high contents of rutin, caffeoylquinic acid, chlorogenic acid, quercetin, iso-quercetin and cathechin using HPLC. Mean of gallic acid and catechin contents (µg /mg extract) were 13.62 and 6.08. The result of the highest total flavonoids (µg quercetin/mg sample extract) with macerating in 50% ethanol at 4th day was 0.6.
Conclusion: We suggested that the result of active ingredients from the flower extract showed no statistically significant difference between macerating with water, 40% ethanol, 50% of ethanol and using ultrasonication method. Ixora chinensis Lamk. flower extract health drink was safe and contained high anti-oxidant active ingredients. Therefore, it would be suitable for developing anti-aging health drink for the future.
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