DIABETES MELLITUS A RISK FACTOR OF GASTRIC CANCER: SYSTEMATIC REVIEW

Authors

  • Mohamad Azwar Aziz General Practitioner, Arjawinangun Regional General Hospital, Indonesia Author
  • Yulia Intan Kania Faculty of Medicine, Muhammadiyah University of Surakarta, Indonesia Author
  • Ilham Aziz Faculty of Medicine, Muhammadiyah University of Surakarta, Indonesia Author
  • Sibli Internal Medicine Consultant, Arjawinangun Regional General Hospital, Indonesia Author

DOI:

https://doi.org/10.61841/cbs35v81

Keywords:

Diabetes mellitus, gastric cancer

Abstract

Background: It is estimated that 500 million individuals globally would have diabetes mellitus (DM) by 2030. A deadly tumor that affects the digestive tract is called gastric cancer (GC). It ranks as the fourth leading cause of cancer death worldwide and the fifth most common kind of cancer. Every year, there are around 700,000 fatalities and one million new cases of GC globally.

Aims: This systematic review is to review the association of diabetes mellitus as a risk factor of gastric cancer.

Methods: This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included.

Result: In the PubMed database, the results of our search brought up 343 articles, whereas the results of our search on SAGEPUB brought up 2178 articles, our search on SCIENCE DIRECT brought up 23102 articles. The results of the search conducted for the last year of 2014 yielded a total 231 articles for PubMed, 1017 articles for SAGEPUB and 12260 articles for SCIENCE DIRECT. In the end, we compiled a total of 5 papers, 2 of which came from PubMed, 1 of which came from SAGEPUB and 2 of which came from SCIENCE DIRECT. We included five research that met the criteria.

Conclusion: In summary, there is no direct association of diabetes mellitus and gastric cancer, but diabetes mellitus can increase the risk factor of gastric cancer cases.

References

Tseng CH, Tseng FH. Diabetes and gastric cancer: The potential links. World J Gastroenterol. 2014 Feb 21;20(7):1701–11.

Shimoyama S. Diabetes mellitus carries a risk of gastric cancer: A metaanalysis. World J Gastroenterol. 2013 Oct 28;19(40):6902–10.

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209–49.

Van Baar ACG, Holleman F, Crenier L, Haidry R, Magee C, Hopkins D, et al. Endoscopic duodenal mucosal resurfacing for the treatment of type 2 diabetes mellitus: One year results from the first international, openlabel, prospective, multicentre study. Gut. 2020 Feb 1;69(2):295–303.

Sekikawa A, Fukui H, Maruo T, Tsumura T, Okabe Y, Osaki Y. Diabetes mellitus increases the risk of early gastric cancer development. Eur J Cancer. 2014;50(12):2065–71.

Takeuchi D, Koide N, Komatsu D, Okumura M, Suzuki A, Miyagawa S. Relationships of obesity and diabetes mellitus to other primary cancers in surgically treated gastric cancer patients. International Journal of Surgery. 2014;12(6):587–93.

Zheng J, Rutegård M, Santoni G, Wallner B, Johansson I, Sund M, et al. Prediabetes and diabetes in relation to risk of gastric adenocarcinoma. Br J Cancer. 2019 Jun 11;120(12):1147–52.

Dabo B, Pelucchi C, Rota M, Jain H, Bertuccio P, Bonzi R, et al. The association between diabetes and gastric cancer: results from the Stomach Cancer Pooling Project Consortium. European Journal of Cancer Prevention. 2022 May 1;31(3):260–9.

Yang HJ, Kang D, Chang Y, Ahn J, Ryu S, Cho J, et al. Diabetes mellitus is associated with an increased risk of gastric cancer: a cohort study. Gastric Cancer. 2020 May 1;23(3):382–90.

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Published

2024-03-13

How to Cite

Aziz, M. A., Kania, Y. I., Aziz, I., & Sibli. (2024). DIABETES MELLITUS A RISK FACTOR OF GASTRIC CANCER: SYSTEMATIC REVIEW. Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 10(3), 149-155. https://doi.org/10.61841/cbs35v81

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