THE SYSTEMATIC REVIEW OF STEM CELL THERAPY FOR STRESS URINARY INCONTINENCE

Authors

  • Muhammad Nanda Satya Pratama Faculty of Medicine, Sultan Agung Islamic University, Semarang, Indonesia Author
  • Herinto Himawan Urologist, Sultan Agung Islamic Hospital, Semarang, Indonesia Author

DOI:

https://doi.org/10.61841/d1xdjn58

Keywords:

Stem cell, stress urinary incontinence.

Abstract

Background: Stem cells have emerged as a novel treatment for many diseases. Stem cells can self-renew and differentiate into other cell types. Adult stem cells are better suited for clinical applications because they can be easily obtained without an invasive procedure, unlike embryonic stem cells (ESCs). Stem-cell therapy for SUI has been studied both preclinically and clinically. Muscle-derived progenitor cells have been used to treat SUI by promoting the regeneration of rhabdomyosphincters.

The aim: This study aims to show stem cell therapy for stress urinary incontinence.

Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and MetaAnalysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.

Result: In the PubMed database the results of our search brought up 133 articles, whereas the results of our search on SagePub brought up 54 articles. The results of the search conducted for the last year of 2013 yielded a total 89 articles for PubMed and 41 articles for SagePub. The result from title screening, a total 9 articles for PubMed and 15 articles for SagePub. In the end, we compiled a total of 10 papers. We included five research that met the criteria.

Conclusion: Comprehensive comparisons between stem cell-based approaches and existing therapies are a prerequisite to rendering stem cell treatment as the predominant strategy for treating intractable urological disorders in the future.

References

Li PC, Ding DC. Stem-cell therapy in stress urinary incontinence: A review. Tzu Chi Med J. 2023;35(2):111.

Gallo F, Ninotta G, Schenone M, Cortese P, Giberti C. Advances in stem cell therapy for male stress urinary incontinence. Expert Opin Biol Ther [Internet]. 2019;19(4):293–300. Available from: https://doi.org/10.1080/14712598.2019.1578343

Schmid FA, Koudy Williams J, Kessler TM, Stenzl A, Aicher WK, Andersson KE, et al. Treatment of stress urinary incontinence with muscle stem cells and stem cell components: Chances, challenges and future prospects. Int J Mol Sci. 2021;22(8).

Liu X, Li T, Zhang J, Lin X, Wang W, Fan X, et al. Mesenchymal stem cell-based therapy for female stress urinary incontinence. Front Cell Dev Biol. 2023;11(January):1–13.

Shin JH, Ryu CM, Yu HY, Shin DM, Choo MS. Current and Future Directions of Stem Cell Therapy for Bladder Dysfunction. Stem Cell Rev Reports. 2020;16(1):82–93.

Daniel E Shumer NJNNPS, Uebelacker LA. 乳鼠心肌提取 HHS Public Access. Physiol Behav.

;176(1):139–48.

Garcia-Arranz M, Alonso-Gregorio S, Fontana-Portella P, Bravo E, Diez Sebastian J, Fernandez-Santos ME, et al. Two phase I/II clinical trials for the treatment of urinary incontinence with autologous mesenchymal stem cells. Stem Cells Transl Med. 2020;9(12):1500–8.

Barakat B, Franke K, Schakaki S, Hijazi S, Hasselhof V, Vögeli TA. Stem cell applications in regenerative medicine for stress urinary incontinence: A review of effectiveness based on clinical trials. Arab J Urol [Internet]. 2020;18(3):194–205. Available from: https://doi.org/10.1080/2090598X.2020.1750864

Williams JK, Dean A, Badlani G, Andersson KE. Regenerative Medicine Therapies for Stress Urinary

Incontinence. J Urol [Internet]. 2016;196(6):1619–26. Available from: http://dx.doi.org/10.1016/j.juro.2016.05.136

Abufaraj M, Xu T, Cao C, Siyam A, Isleem U, Massad A, et al. Prevalence and trends in urinary incontinence among women in the United States, 2005–2018. Am J Obstet Gynecol [Internet]. 2021;225(2):166.e1-166.e12. Available from: https://doi.org/10.1016/j.ajog.2021.03.016

Zhou HH, Shu B, Liu TZ, Wang XH, Yang ZH, Guo YL. Association between parity and the risk for urinary incontinence in women. Medicine (Baltimore). 2018;97(28):e11443.

Seval MM, Koyuncu K. Current status of stem cell treatments and innovative approaches for stress urinary incontinence. Front Med. 2022;9(December 2009).

Maiborodin I, Yarin G, Marchukov S, Pichigina A, Lapii G, Krasil’nikov S, et al. Cell Technologies in the Stress Urinary Incontinence Correction. Biomedicines. 2022;10(2):1–7.

Tran C, Damaser MS. The potential role of stem cells in the treatment of urinary incontinence. Ther Adv Urol. 2015;7(1):22–40.

Klapper-Goldstein H, Tamam S, Sade S, Weintraub AY. A systematic review of stem cell therapy treatment for women suffering from stress urinary incontinence. Int J Gynecol Obstet. 2022;157(1):19–30.

Mousa NA. Stem cell applications for pathologies of the urinary bladder. World J Stem Cells. 2015;7(5):815.

Downloads

Published

2024-03-04

How to Cite

Pratama, M. N. S., & Himawan, H. (2024). THE SYSTEMATIC REVIEW OF STEM CELL THERAPY FOR STRESS URINARY INCONTINENCE. Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 10(3), 27-33. https://doi.org/10.61841/d1xdjn58

Similar Articles

11-20 of 420

You may also start an advanced similarity search for this article.