THE ASSOCIATION BETWEEN MALIGNANT OTITIS EXTERNA AND DIABETES MELLITUS: A SYSTEMATIC REVIEW

Authors

  • Bayu Setyo Nugroho Waled Regional Hospital, Cirebon Regency, Indonesia Author

DOI:

https://doi.org/10.61841/wkjy2x25

Keywords:

Malignant otitis externa, diabetes mellitus

Abstract

Background: Diabetes mellitus is one of the risk factors for malignant otitis externa. There are very few studies on the disease and there is a need to pool the prior studies to highlight the characteristics of the disease.

Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and MetaAnalysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.

Result: In the PubMed database, the results of our search brought up 177 articles, whereas the results of our search on SagePub brought up 56 articles. The results of the search conducted for the last year of 2013 yielded a total 59 articles for PubMed and 12 articles for SagePub. In the end, we compiled a total of  4 papers, 3 of which came from PubMed and 1 of which came from SagePub. We included five research that met the criteria.

Conclusion: MEO is an aggressive type of external otitis leading to osteomyelitis of the skull base bone. The usual microorganism involved is Pseudomonas species, and it usually affects individuals with diabetes mellitus. Treatment of the disease has changed over the years, today following conservative treatment modalities with antibiotics and conducting surgery under special circumstances. MEO is a rare but fatal disease, and the specialists involved in its diagnosis and treatment, namely ENT surgeons and diabetes specialists, should be aware of it.

References

Tsilivigkos C, Avramidis K, Ferekidis E, Doupis J. Malignant External Otitis: What the Diabetes Specialist Should Know—A Narrative Review. Diabetes Ther [Internet]. 2023 Apr [cited 2023 Dec3];14(4):629–38. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064349/

Grandis JR, Edwards MS, Durand ML. Malignant (necrotizing) external otitis. UpToDate [Internet]. 2022 [cited 2023 Dec 3]; Available from: https://www.uptodate.com/contents/malignant-necrotizingexternal-otitis#topicContent

Habra B, Mghari G El, Ansari N El. Malignant external otitis in diabetic patients. Endocrinology & Metabolism International Journal. 2018 May 7;6(3).

Korbel L, Spencer JD. Diabetes Mellitus and Infection: An Evaluation of Hospital Utilization and Management Costs in the United States. J Diabetes Complications [Internet]. 2016 [cited 2023 Dec

;29(2):192–5. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333016/

McDonald HI, Millett ERC, Sinclair A, Thomas SL. New estimates of the burden of acute communityacquired infections among older people with diabetes mellitus: a retrospective cohort study using linked electronic health records. Diabet Med. 2014;31(5):606–14.

Yang TH, Xirasagar S, Cheng YF, Wu CS, Kao YW, Shia BC, et al. Malignant Otitis Externa is

Associated with Diabetes: A Population-Based Case-Control Study Tzong-Hann Yang 1 2 3, Sudha Xirasagar 4, . Ann Otol Rhinol Laryngol [Internet]. 2020 Jun [cited 2023 Dec 3];129(5):585–90. Available from: https://pubmed.ncbi.nlm.nih.gov/31976744/

Peled C, Sadeh R, El-Saied S, Novack V, Kaplan DM. Diabetes and glycemic control in necrotizing otitis externa (NOE). Eur Arch Otorhinolaryngol [Internet]. 2022 [cited 2023 Dec 3];279(3):1269–75. Available from: https://pubmed.ncbi.nlm.nih.gov/33792784/

Guerrero-Espejo A, Valenciano-Moreno I, Ramirez-Llorens R, Perez-Monteagudo P. Malignant external otitis in Spain. Acta Otorrhinolaringol Esp. 2017;68(1):23–8.

Jain A, Sharma V, Fatima SS. Malignant Otitis Externa: Diagnostic Dilemma in a Patient with Atypical Presentation. Indian J Otolaryngol Head Neck Surg [Internet]. 2022 [cited 2023 Dec 3];74:3589–91. Available from: https://pubmed.ncbi.nlm.nih.gov/36742753/

Lee SK, Lee SA, Seon SW, Jung JH, Choi JY, Kim BG. Analysis of Prognostic Factors in Malignant External Otitis. Clin Exp Otorhinolaryngol [Internet]. 2017 [cited 2023 Dec 3];10(3):228–35. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545692/

Gonzalez JLT, Suarez LLR, de Leon JEH. Malignant otitis externa: An updated review. Am J Otolaryngol. 2021;42(2).

Yigider AP, Ovunc O, Sunter AV, Cermik TF, Yigit O. Malignant Otitis Externa: How to Monitor the Disease in Outcome Estimation? Medeni Med J [Internet]. 2021 [cited 2023 Dec 3];36(1):23–9.

Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020189/

Byun YJ, Patel J, Nguyen SA, Lambert PR. Hyperbaric oxygen therapy in malignant otitis externa: A systematic review of the literature. World J Otorhinolaryngol Head Neck Surg [Internet]. 2021 Oct [cited 2023 Dec 3];7(4):296–302. Available from:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486695/

Honnurappa V, Ramdass S, Mahajan N, Vijayendra VK, Redleaf M. Effective Inexpensive Management of Necrotizing Otitis Externa Is Possible in Resource-Poor Settings. Ann Otol Rhinol Laryngol. 2019;128(9):848–54.

Pasquel FJ, Lansang MC, Dhatariya K, Umpierrez GE. Management of diabetes and hyperglycaemia in the hospital. Lancet Diabetes Endocrinol. 2021 Mar;9(3):174–88.

Downloads

Published

2023-12-03

How to Cite

Nugroho, B. S. (2023). THE ASSOCIATION BETWEEN MALIGNANT OTITIS EXTERNA AND DIABETES MELLITUS: A SYSTEMATIC REVIEW. Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 9(12), 8-15. https://doi.org/10.61841/wkjy2x25