THE SYSTEMATIC REVIEW OF NON-OPIOID ANALGESICS IN ADULTS AFTER MAJOR SURGERY

Authors

  • Fajar Nurochman Sidik Jampangkulon Regional General Hospital, Sukabumi, Indonesia Author
  • Dhimas Muhammad Suharyo Primaya General Hospital, Sukabumi, Indonesia Author
  • Hipni Solehudin Jampangkulon Regional General Hospital, Sukabumi, Indonesia Author
  • Fitria Lesmana Putri Jampangkulon Community Health Center, Sukabumi, Indonesia Author

DOI:

https://doi.org/10.61841/yh9qzz65

Keywords:

Non-opioid analgetic, major surgery

Abstract

Background: Following surgery, chronic postsurgical discomfort is frequent. Finding non-opioid analgesics that may be able to stop persistent pain following surgery is crucial, even if these trials frequently lack sufficient funding.

Aims: This systematic review is to review the effects of non-opioid analgesics in adults after major surgery

Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and MetaAnalysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed and SCIENCE DIRECT, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.

Result: In the PubMed database, the results of our search brought up 234 articles, whereas the results of our search on SCIENCE DIRECT brought up 803 articles. The results of the search conducted for the last year of 2014 yielded a total 67 articles for PubMed and 29 articles for SCIENCE DIRECT. In the end, we compiled a total of 6 papers, 5 of which came from PubMed and 1 of which came from SCIENCE DIRECT. We included six research that met the criteria.

Conclusion: In summary, this systematic review contains the postoperative outcomes in patients after treated with intravein non opioid analgetics after surgery than in controls in terms of 24 hours post operative of opioid use, the pain score, hopitalization perior and the occurrence of opioid related adverse events.

References

Mwachiro M, Mwachiro E, Wachu MA, Koske W, Thure L, Parker RK, et al. Assessing Post-operative Pain with Self-reports via the Jerrycan Pain Scale in Rural Kenya. World J Surg. 2020;44(11):3636–42.

Orhurhu V, Orman S, Peck J, Urits I, Orhurhu MS, Jones MR, et al. Carpal tunnel release surgery- a systematic review of open and endoscopic approaches. Anesth Pain Med. 2020 Dec 1;10(6):1–12.

Marcadis AR, Spencer T, Sleeman D, Velazquez O, Lew JI. Case distributions in general surgery residency: Subspecialization occurs before fellowship. Surgery. 2020;167(4):717–23.

Schwenk ES, Mariano ER. Designing the ideal perioperative pain management plan starts with multimodal analgesia. Vol. 71, Korean Journal of Anesthesiology. Korean Society of Anesthesiologists; 2018. p. 345–52.

kumar TS, Muthuraman M, Krishnakumar R. Effect of the Raga Ananda Bhairavi in Post Operative Pain Relief Management. Indian Journal of Surgery. 2014 Nov 23;76(5):363–70.

Nowak H, Zech N, Asmussen S, Rahmel T, Tryba M, Oprea G, et al. Effect of therapeutic suggestions during general anaesthesia on postoperative pain and opioid use: Multicentre randomised controlled trial. The BMJ. 2020 Dec 10;371.

Sierżantowicz R, Lewko J, Bitiucka D, Lewko K, Misiak B, Ładny JR. Evaluation of pain management after surgery: An observational study. Medicina (Lithuania). 2020 Feb 1;56(2).

Beverly A, Kaye AD, Ljungqvist O, Urman RD. Essential Elements of Multimodal Analgesia in Enhanced Recovery After Surgery (ERAS) Guidelines. Anesthesiol Clin. 2017;35(2):115–43.

Beloeil H, Albaladejo P, Sion A, Durand M, Martinez V, Lasocki S, et al. Multicentre, prospective, doubleblind, randomised controlled clinical trial comparing different non-opioid analgesic combinations with morphine for postoperative analgesia: the OCTOPUS study. Br J Anaesth. 2019 Jun 1;122(6):e98–106.

Takeda Y, Fukunishi S, Nishio S, Yoshiya S, Hashimoto K, Simura Y. Evaluating the Effect of Intravenous Acetaminophen in Multimodal Analgesia After Total Hip Arthroplasty: A Randomized Controlled Trial. J Arthroplasty. 2019;34(6):1155–61.

Bollinger AJ, Butler PD, Nies MS, Sietsema DL, Jones CB, Endres TJ. Is Scheduled Intravenous

Acetaminophen Effective in the Pain Management Protocol of Geriatric Hip Fractures? Geriatr Orthop Surg Rehabil. 2015 Sep 18;6(3):202–8.

Connolly KP, Kleinman RS, Stevenson KL, Neuman MD, Mehta SN. Delirium Reduced With Intravenous Acetaminophen in Geriatric Hip Fracture Patients. J Am Acad Orthop Surg. 2020 Apr 15;28(8):325–31.

Xiao K, Yu L, Xiao W, Peng H, Bian Y, Wu Z, et al. Pain Management Using Perioperative Administration of Parecoxib for Total Hip Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial. Pain Physician. 2019;22(6):575–82.

Wang D, Liao C, Tian Y, Zheng T, Ye H, Yu Z, et al. Analgesic efficacy of an opioid-free postoperative pain management strategy versus a conventional opioid-based strategy following open major hepatectomy: an openlabel, randomised, controlled, non-inferiority trial [Internet]. 2023. Available from: www.uptodate.com/

Doleman B, Mathiesen O, Sutton AJ, Cooper NJ, Lund JN, Williams JP. Non-opioid analgesics for the prevention of chronic postsurgical pain: a systematic review and network meta-analysis. Vol. 130, British Journal of Anaesthesia. Elsevier Ltd; 2023. p. 719–28.

Jain Y, Lanjewar R, Lamture Y, Bawiskar D. Evaluation of Different Approaches for Pain Management in Postoperative General Surgery Patients: A Comprehensive Review. Cureus. 2023 Nov 9;

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Published

2024-02-12

How to Cite

Sidik, F. N., Suharyo, D. M., Solehudin, H., & Putri, F. L. (2024). THE SYSTEMATIC REVIEW OF NON-OPIOID ANALGESICS IN ADULTS AFTER MAJOR SURGERY. Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 10(2), 112-119. https://doi.org/10.61841/yh9qzz65

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