INNOVATIVE NUTRITIONAL APPROACH TO ATTENUATE THE PROGRESSION OF HIV TO AIDS AMONG PEOPLE LIVING WITH HIV (PLWH): A STUDY BASED IN ABUJA, NIGERIA
DOI:
https://doi.org/10.53555/nnmhs.v5i1.600Abstract
Human Immunodeficiency Virus (HIV) is a severely infectious and fast replicating retro-virus, genetically made–up of a single stranded RNA molecule, which impairs and deteriorates the immune system’s cells (WHO, 2006; AIDS, 2009; WHO, 2013; Amlogu et al., 2013; CDC, 2014). Acquired immunodeficiency syndrome (AIDS) is a progressive deterioration of the immune status of the individual. It is characterised by the progressive depletion of the CD4 T- lymphocyte population (cells that produces a specific immunity to a particular antigen), which represents a major target of viral infection by the causative HIV (Table 1.1) (Vajpayee et al., 2005; Amlogu, et al., 2012). World Health Organization (WHO, 2006) provides a simplified HIV case definition designed for reporting and surveillance (Box 1.1).
The aetiology of AIDS has been identified as HIV-1 and HIV-2 (FMOH, 2007). This virus belongs to the Lentivirus group and Retroviridae family (Figure 1.1). The Family Retroviridae of viruses includes three sub-families: Oncovirinae, Lentivirinae and Spurnavirinae. All the members of the family contain an enzyme called reverse transcriptase that is used for the synthesis of proviral DNA from the infecting viral RNA.
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